A client who has hemophilia A and his wife, who is not a carrier of the disease, wish to start a family. In discussing the risk factors of transmitting hemophilia to his children, it is important to explain that
A) none of his children are likely to have hemophilia.
B) all of his children will be carriers.
C) all of his sons will have hemophilia.
D) 50% of his children are at risk for developing the disease.

Question

Quizplus · Accepted Answer

Hemophilia is genetically transmitted in a sex-linked (X chromosome) recessive pattern. Female carriers will transmit the defective gene to 50% of their sons, and 50% of their daughters will be carriers. Males express the bleeding disorder. Males with hemophilia transmit the gene to all of their daughters, who become carriers, but to none of their sons. A female can be a hemophiliac in the rare instance of a male hemophiliac producing a daughter with a mother who is a carrier.

A Client Who Has Hemophilia a and His Wife, Who