Which of the following is the best definition of epitope?
A)specific regions on antigens that interact with T-cell receptors
B)specific regions on antigens that interact with MHC class molecules
C)specific regions on antigens that interact with haptens
D)specific regions on antigens that interact with antibodies
E)specific regions on antigens that interact with perforins

Question

Quizplus · Accepted Answer

An epitope is a specific region on an antigen that interacts with an antibody. This interaction leads to the production of specific antibodies against the antigen. Other choices are incorrect as T-cell receptors interact with MHC molecules (A and B), haptens are not antigens but small molecules that can bind to larger proteins to elicit an immune response (C), and perforins are proteins released from cytotoxic T-cells that target infected cells, not antigens (E).

Which of the Following Is the Best Definition of Epitope