The classical pathway for complement activation is initiated by
A)lipid-carbohydrate complexes and C3.
B)C5-C9.
C)antigen-antibody reactions.
D)factors released from phagocytes.
E)factors released from damaged tissues.

Question

Quizplus · Accepted Answer

The classical pathway for complement activation is initiated by antigen-antibody reactions. When an antibody binds to its specific antigen, it undergoes a conformational change that exposes a binding site for C1, a component of the complement system. This initiates a cascade of reactions that leads to the activation of C3, the central component of the complement system.

The Classical Pathway for Complement Activation Is Initiated by