Injectable drugs are tested for endotoxins by
A)the Limulus amoebocyte lysate test.
B)counting the viable bacteria.
C)filtering out the cells.
D)looking for turbidity.
E)culturing bacteria.

Question

Quizplus · Accepted Answer

The Limulus amoebocyte lysate (LAL) test is the most commonly used method for testing injectable drugs for endotoxins. This test measures the presence of endotoxins by detecting the clotting reaction that occurs when LAL from horseshoe crab blood is exposed to endotoxins. The LAL test is highly sensitive and specific for the detection of endotoxins and is approved by regulatory agencies such as the FDA for use in testing injectable drugs.

Injectable Drugs Are Tested for Endotoxins by