DTT (dithiothreitol)would be useful in the identification of which of the following antibodies? A)Anti-Js^a B)Anti-Kp^b C)Anti-Vel D)Anti-K

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Anti-Kp^b is a high-frequency antigen in the Kell system.If an Anti-Kp^b is suspected,the panel cells could be treated with DTT and the sample retested.If all reactions are eliminated,the anti-Kp^b is confirmed and other underlying alloantibodies are ruled out.Although K would also be destroyed by DTT,there are sufficient negative cells on the panel to determine if underlying antibodies exist and confirm the specificity.

DTT (Dithiothreitol)would Be Useful in the Identification of Which of the Following