Which of the following statements about the chloride shift is false?
A)It involves a movement of chloride ion into RBCs.
B)It depends on the chloride-bicarbonate countertransporter.
C)It involves a movement of bicarbonate ions into the plasma.
D)It is driven by a rise in PCO₂.
E)It causes RBCs to swell.

Question

Quizplus · Accepted Answer

The chloride shift causes RBCs to shrink, not swell. This occurs because chloride ions move into the RBCs in exchange for bicarbonate ions, which leaves the RBCs with a net negative charge, causing water to move out of the cell and resulting in shrinking.

Which of the Following Statements About the Chloride Shift Is