The following are important steps in the process of endochondral ossification. 1.Enlarged chondrocytes die.
2)Osteoblasts replace calcified cartilage with spongy bone.
3)Chondrocytes enlarge and the surrounding matrix begins to calcify.
4)Blood vessels invade the perichondrium.
5)Perichondrial cells become osteoblasts and produce a thin shell of bone.
The correct order for these events is
A)3,1,5,4,2
B)1,3,5,4,2
C)1,5,3,4,2
D)2,3,1,5,4
E)3,1,4,5,2

Question

Quizplus · Accepted Answer

Endochondral ossification begins with chondrocytes enlarging and the matrix calcifying (3), followed by the death of enlarged chondrocytes (1). Blood vessels then invade the perichondrium (4), perichondrial cells become osteoblasts and produce a thin shell of bone (5), and finally, osteoblasts replace calcified cartilage with spongy bone (2).

The Following Are Important Steps in the Process of Endochondral