Which Statement Explains What Happens to Toxic Substances After Detoxification

Which statement explains what happens to toxic substances after detoxification by liver cells?

A) They are used to increase pH for optimum amylase function.
B) They are used to dilute food and other substances and facilitate mixing of foods in the small intestine.
C) Small amounts are carried by mucus and sodium bicarbonate to the small intestine for use in digestion.
D) They are changed into nontoxic compounds by a series of chemical reactions.