Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to
A) disruption of mitotic spindle formation.
B) inhibition of regulatory protein phosphorylation.
C) suppression of cyclin production.
D) myosin denaturation and inhibition of cleavage furrow formation.
E) inhibition of DNA synthesis.

Question

Quizplus · Accepted Answer

Vinblastine interferes with the assembly of microtubules, which are crucial components of the mitotic spindle. Therefore, the drug's effectiveness must be related to the disruption of mitotic spindle formation.

Vinblastine Is a Standard Chemotherapeutic Drug Used to Treat Cancer