Cells from an advanced malignant tumour most often have very abnormal chromosomes, and often an abnormal total number of chromosomes. Why might this occur?
A)Cancer cells are no longer density dependent.
B)Cancer cells are no longer anchorage dependent.
C)Chromosomally abnormal cells can still go through cell cycle checkpoints.
D)Chromosomally abnormal cells still have normal metabolism.
E)Transformation introduces new chromosomes into cells.

Question

Quizplus · Accepted Answer

Chromosomally abnormal cells can still go through cell cycle checkpoints, leading to their continued proliferation and accumulation of additional chromosomal abnormalities. This can ultimately result in the abnormal total number and structures of chromosomes seen in advanced malignant tumours.

Cells from an Advanced Malignant Tumour Most Often Have Very