Vitamin-responsive forms of methylmalonic acidemia are treated with pharmacological amounts of what vitamin?
A) biotin
B) B12
C) B6
D) riboflavin
E) thiamin

Question

Vitamin-responsive forms of methylmalonic acidemia are treated with pharmacological amounts of what vitamin?​
A) ​biotin
B) ​B12
C) ​B6
D) ​ riboflavin
E) thiamin

Quizplus · Accepted Answer

Vitamin B12 is the only pharmacological treatment for vitamin-responsive forms of methylmalonic acidemia. It is given in high doses to bypass the metabolic block in the conversion of methylmalonyl-CoA to succinyl-CoA.

Vitamin-Responsive Forms of Methylmalonic Acidemia Are Treated with Pharmacological Amounts