For intramembranous ossification to take place, which of the following is necessary?
A) A bone collar forms around the cartilage model.
B) An ossification center forms in the fibrous connective tissue.
C) The cartilage matrix begins to deteriorate.
D) A medullary cavity forms.

Question

Quizplus · Accepted Answer

Intramembranous ossification occurs when bone forms directly from mesenchymal (undifferentiated) connective tissue. The process begins with an ossification center forming within fibrous connective tissue, which then undergoes differentiation into osteoblasts, which lay down bone matrix. A bone collar forming around a cartilage model is a characteristic of endochondral ossification, not intramembranous ossification. The deterioration of cartilage matrix is also a characteristic of endochondral ossification, not intramembranous ossification. The formation of a medullary cavity is a characteristic of endochondral ossification, which occurs within the diaphysis of long bones.

For Intramembranous Ossification to Take Place, Which of the Following