Anytime the [HCO₃⁻]/[CO₂] ratio falls below 20/1 indicates an acidosis condition.

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A [HCO₃⁻]/[CO₂] ratio below 20/1 indicates an imbalance in acid-base homeostasis, specifically respiratory acidosis. This means that there is too much CO₂ in the bloodstream and not enough bicarbonate, which can lead to a decrease in blood pH and a range of physiological problems. Therefore, a ratio below 20/1 indicates an acidosis condition.

Anytime the [HCO₃⁻]/[CO₂] Ratio Falls Below 20/1 Indicates an Acidosis