Unassisted membrane transport can sometimes require the cell to expend energy.

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Unassisted membrane transport, also known as passive transport, does not require the cell to expend energy. Examples of unassisted membrane transport include simple diffusion and facilitated diffusion. However, active transport does require the cell to expend energy to move substances against their concentration gradient. Examples of active transport include the sodium-potassium pump and endocytosis/exocytosis.

Unassisted Membrane Transport Can Sometimes Require the Cell to Expend