The following are important steps in the process of endochondral ossification.
1) Enlarged chondrocytes die.
2) Osteoblasts replace calcified cartilage with spongy bone.
3) Chondrocytes enlarge and the surrounding matrix begins to calcify.
4) Blood vessels penetrate the cartilage.
5) Perichondrial cells become osteoblasts and produce a thin shell of bone.
The correct order for these events is
A) 3, 1, 5, 4, 2.
B) 1, 3, 5, 4, 2.
C) 1, 5, 3, 4, 2.
D) 2, 3, 1, 5, 4.
E) 3, 1, 4, 5, 2.

Question

Quizplus · Accepted Answer

The correct order of events in endochondral ossification is: chondrocytes enlarge and the surrounding matrix begins to calcify (3), enlarged chondrocytes die (1), perichondrial cells become osteoblasts and produce a thin shell of bone (5), blood vessels penetrate the cartilage (4), and osteoblasts replace calcified cartilage with spongy bone (2).

The Following Are Important Steps in the Process of Endochondral