Which bone cells are responsive to parathyroid hormone, produce osteocalcin when stimulated by 1,25-dihydroxyvitamin D, and synthesize osteoid?
A)Osteoclasts
B)Osteocytes
C)Fibrocytes
D)Osteoblasts

Question

Quizplus · Accepted Answer

Osteoblasts are cells derived from mesenchymal stem cells. Osteoblasts produce several substances, including osteocalcin, TGF-b (a growth inhibitor for many cells), macrophage colony-stimulating factor, receptor activator of nuclear factor kB-ligand, OPG, and bone matrix and osteocalcin when stimulated by 1,25-dihydroxyvitamin D. Osteoblasts are active on the outer surface of bones, where they form a single layer of cells. They bring about the formation of new bone by their synthesis of osteoid (nonmineralized bone matrix).

Which Bone Cells Are Responsive to Parathyroid Hormone, Produce Osteocalcin