Which statement is false regarding the pathophysiology of acute pancreatitis?
A)Pancreatic acinar cells metabolize ethanol, which generates toxic metabolites.
B)Injury to the pancreatic acinar cells permits leakage of pancreatic enzymes that digest pancreatic tissue.
C)Acute pancreatitis is an autoimmune disease in which IgG coats the pancreatic acinar cells so they are destroyed by the pancreatic enzymes.
D)When gallstones are present, bile flows into the pancreas, contributing to attacks.

Question

Quizplus · Accepted Answer

Acute pancreatitis (acute hemorrhagic pancreatitis) is initiated by intrapancreatic activation of proteases. The pancreatic acinar cell metabolizes ethanol with the generation of toxic metabolites. The most common theory is that pancreatitis develops because of an injury or disruption of pancreatic acinar cells, which permits leakage of pancreatic enzymes (trypsin, chymotrypsin, and elastase) into pancreatic tissue. Activated proteolases (trypsin and elastase) and lipases break down tissue and cell membranes, causing inflammation, edema, vascular damage, hemorrhage, necrosis, and fibrosis.

Which Statement Is False Regarding the Pathophysiology of Acute Pancreatitis