In a type II hypersensitivity reaction, that is an antibody-dependent cell-mediated cytotoxicity (ADCC), target cells are destroyed by:
A)complement-mediated cell lysis.
B)phagocytosis by macrophages.
C)neutrophil granules and toxic oxygen products.
D)natural killer cells.

Question

Quizplus · Accepted Answer

This mechanism involves a subpopulation of cytotoxic cells that are not antigen specific (natural killer [NK] cells). Antibody on the target cell is recognized by Fc receptors on the NK cells, which release toxic substances that destroy the target cell.

In a Type II Hypersensitivity Reaction, That Is an Antibody-Dependent