When the nurse is administering a vesicant chemotherapeutic agent intravenously, an important consideration is to

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Swelling at the site may indicate extravasation, and the IV should be stopped immediately. The medication generally should be given slowly to avoid irritation of the vein. The size of the catheter is not as important as administration of vesicants into a running IV line to allow dilution of the chemotherapeutic drug. These medications can be given through peripheral lines, although central vascular access devices (CVADs) are preferred.

When the Nurse Is Administering a Vesicant Chemotherapeutic Agent Intravenously