Dr. O'Reilly is trying to produce hyperpolarization in the neurons in her laboratory. What should she do?
A) Use a microelectrode to apply a positive charge
B) Use a microelectrode to apply a negative charge
C) Add a drug that will increase the membrane's permeability to sodium
D) Add a drug that will decrease the membrane's permeability to potassium

Question

Quizplus · Accepted Answer

Hyperpolarization refers to an increase in the membrane potential difference, meaning that the inside of the neuron becomes more negative relative to the outside. To achieve hyperpolarization, a negative charge must be applied to the neuron. Therefore, the best choice is to use a microelectrode to apply a negative charge (choice B).

Dr O'Reilly Is Trying to Produce Hyperpolarization in the Neurons