Damage to the glomerular filtration membrane allowing proteins into the capsular space would result in allof the following except
A) an increase in capsular colloid osmotic pressure.
B) a decrease in blood colloid osmotic pressure.
C) an increase in net filtration pressure.
D) an increase in GFR and fluid loss.
E) a decrease in capsular hydrostatic pressure.

Question

Quizplus · Accepted Answer

Damage to the glomerular filtration membrane allowing proteins into the capsular space would indeed result in an increase in capsular colloid osmotic pressure (A) because proteins that normally do not pass into the filtrate would do so, attracting water and increasing the osmotic pressure in the capsular space. This would also lead to a decrease in blood colloid osmotic pressure (B) because the proteins, which contribute to the osmotic pressure in the blood, are lost into the filtrate. Consequently, there would be an increase in net filtration pressure (C) because the gradient for filtration is enhanced by the higher osmotic pressure in the capsular space and the lower osmotic pressure in the blood. This would likely result in an increase in the glomerular filtration rate (GFR) and fluid loss into the urine (D) because the forces favoring filtration are increased. However, the presence of proteins in the capsular space would not lead to a decrease in capsular hydrostatic pressure (E); if anything, it might increase due to the increased volume of filtrate or remain unchanged.

Damage to the Glomerular Filtration Membrane Allowing Proteins into the Capsular