Which of the following experimental procedures is most likely to hasten mRNA degradation in a eukaryotic cell?
A)enzymatic shortening of the poly(A)tail
B)removal of the 5' cap
C)methylation of C nucleotides
D)memethylation of histones
E)removal of one or more exons

Question

Quizplus · Accepted Answer

Removal of the 5' cap is likely to hasten mRNA degradation because the cap protects the mRNA from degradation in the cytoplasm. Without the cap, the mRNA is more susceptible to degradation. Enzymatic shortening of the poly(A) tail may also hasten mRNA degradation, but it is not the most likely option as the poly(A) tail protects the mRNA from degradation. Methylation of C nucleotides, demethylation of histones, and removal of one or more exons are not directly involved in mRNA degradation.

Which of the Following Experimental Procedures Is Most Likely to Hasten