Why Is It Important to Know What Microscopy Method Was

Why is it important to know what microscopy method was used to prepare the images you wish to study?

A) so that you can judge whether the images you are seeing are of cells or of organelles
B) so that you can make a judgment about the likelihood of artifacts having been introduced in the preparation
C) so that you can decide whether the image is actually of the size described
D) so that you can know whether to view the image in color or not
E) so that you can interpret the correct biochemical process that is occurring