The proximity effect of speeding an enzyme-catalyzed reaction is explained by ________.
A)a large loss of entropy when reactive groups are brought close to each other
B)a large gain in entropy due to binding of the substrate
C)a conversion of a reaction from endergonic to exergonic
D)increasing the flexibility of the substrate by increasing its degrees of freedom of rotation

Question

Quizplus · Accepted Answer

The proximity effect refers to the increased rate of an enzyme-catalyzed reaction due to the reactive groups being brought close together. This is due to a large loss of entropy when the reactive groups are brought close to each other, which allows for the formation of more stable transition states and a faster overall reaction rate.

The Proximity Effect of Speeding an Enzyme-Catalyzed Reaction Is Explained