Rho-dependent termination
A)is due to destabilization of the RNA-DNA hybrid.
B)is due to indirect contact between the transcription complex and rho as rho binds RNA.
C)may cause the RNA polymerase to bind to template DNA.
D)All of the above.

Question

Quizplus · Accepted Answer

Rho-dependent termination occurs when the rho protein binds to the RNA transcript and moves along it towards the RNA polymerase. As it does so, it destabilizes the RNA-DNA hybrid, causing the RNA polymerase to release the transcript and detach from the DNA. There is no direct contact between the transcription complex and rho; the interaction is mediated through the RNA transcript. There is also no evidence that rho-dependent termination causes RNA polymerase to bind to template DNA. Therefore, the correct choice is A.

Rho-Dependent Termination