The mechanism of pyruvate dehydrogenase complex is an example of channeling.

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Pyruvate dehydrogenase complex is an example of channeling, where the products from one enzyme reaction are directly passed to the next enzyme within a complex, without being released into the bulk solution. In this complex, pyruvate is channeled through three consecutive enzymes to generate acetyl-CoA. This process is essential for the efficient utilization of metabolic intermediates and helps prevent loss of intermediates and wasteful side reactions.

The Mechanism of Pyruvate Dehydrogenase Complex Is an Example of Channeling