Ribosomes that do not anchor to the surface of the rough endoplasmic reticulum during translation most probably
A)are synthesizing cytoplasmic proteins.
B)have a defect in ribosomal proteins that allow attachment to the ER.
C)have a signal/trafficking error.
D)do not make the appropriate anchor protein.
E)all of the above

Question

Quizplus · Accepted Answer

Ribosomes that do not anchor to the surface of the rough endoplasmic reticulum during translation are likely synthesizing cytoplasmic proteins, which do not require attachment to the ER for proper folding and processing. Choices B, C, and D are all incorrect as they suggest errors or defects in the ribosomal proteins, signaling pathways, or anchor proteins, respectively, which would prevent attachment to the ER. There is no indication in the question stem that such errors or defects are present.

Ribosomes That Do Not Anchor to the Surface of the Rough