Beadle discovered that metabolic pathways are studied most effectively using which of the following techniques?
A)creating multiple gene mutations resulting in nonfunctional enzymes specific to a metabolic pathway
B)adding additional intermediates of the metabolic pathway
C)removing all intermediates of the metabolic pathway
D)creating single gene mutations resulting in nonfunctional enzymes specific to a metabolic pathway

Question

Quizplus · Accepted Answer

Creating single gene mutations resulting in nonfunctional enzymes specific to a metabolic pathway is the most effective technique for studying metabolic pathways because it allows for the specific disruption of one enzyme in the pathway, which can lead to a buildup of intermediates and allow researchers to identify the function of the disrupted enzyme. This technique is also less disruptive overall to the pathway compared to completely removing or adding intermediates.

Beadle Discovered That Metabolic Pathways Are Studied Most Effectively Using