What is the purpose of b₂-microglobulin associated with MHC class I molecules?
A) Stabilization
B) Interacts with T cell
C) Anchors to membrane
D) Scaffolding molecule between TAP and MHC class I molecule

Question

Quizplus · Accepted Answer

The purpose of b₂-microglobulin is to stabilize the MHC class I molecule. The MHC class I molecule has an a-chain with a transmembrane domain, and tapasin serves as a connection to TAP proteins, as well as other supporting proteins, such as calreticulin and ERp57. b₂-Microglobulin is not in a position in the MHC class I structure to interact with a T cell.

What Is the Purpose of B₂-Microglobulin Associated with MHC Class