Atrial natriuretic factor (ANF) serves to reduce hemodynamic load. In the embryonic heart, the gene for ANF is expressed in both the atrium and the ventricle. After birth, _____expression of the gene is down regulated. Cardiac hypertrophy is associated with a(n) _________ of ANF gene expression.
A) Atrial; Decrease
B) Atrial; Increase
C) Ventricular; Decrease
D) Ventricular; Increase

Question

Quizplus · Accepted Answer

In the embryonic heart, ANF is expressed in both atria and ventricles, but after birth, its expression is downregulated in the ventricles. Cardiac hypertrophy is associated with an increase in ANF gene expression.

Atrial Natriuretic Factor (ANF) Serves to Reduce Hemodynamic Load