The initiation site binds a purine nucleotide base pairing with the +1 base exposed within the open promoter complex.Which of the following is where the second base is added?
A)to the 5'-C of the first base
B)to the 3'-C of the first base
C)to the 5'-O of the first base
D)to the 3'-O of the first base

Question

Quizplus · Accepted Answer

The second base is added to the 3'-O (3'-hydroxyl group) of the first base during RNA synthesis, as nucleotides are added to the 3' end of the growing RNA chain.

The Initiation Site Binds a Purine Nucleotide Base Pairing with the +1