Enzymatic ribonucleotide reduction is accomplished via a free radical mechanism.Which of the following statements regarding this process is correct?
A)The substrate specificity site on the R1 homodimer determines if the enzyme is active or inactive.
B)R2 has a single active site containing 2 Fe atoms that generate the free radicals.
C)R2,but not R1,functions in the delivery of reducing equivalents.
D)R2 homodimer carries 2 regulatory sites.

Question

Quizplus · Accepted Answer

R2 has a single active site containing 2 Fe atoms that generate the free radicals. This active site is responsible for the reduction of ribonucleotides to deoxyribonucleotides.

Enzymatic Ribonucleotide Reduction Is Accomplished Via a Free Radical Mechanism