What is the importance of the purine nucleoside cycle?
A)It participates in the conversion of purines into pyrimidines.
B)It generates fumarate,which inhibits the formation of AMP from IMP.
C)It provides fumarate as an anaplerotic enhancement of the citric acid cycle.
D)It inhibits the citric acid cycle in skeletal muscles.

Question

What is the importance of the purine nucleoside cycle?
A)It participates in the conversion of purines into pyrimidines.
B)It generates fumarate,which inhibits the formation of AMP from IMP.
C)It provides fumarate as an anaplerotic enhancement of the citric acid cycle.
D)It inhibits the citric acid cycle in skeletal muscles.

Quizplus · Accepted Answer

The purine nucleoside cycle provides fumarate as an anaplerotic enhancement of the citric acid cycle. Anaplerosis refers to the replenishment of intermediates in a metabolic pathway. Fumarate is a key intermediate in the citric acid cycle, and its availability can influence the activity of the cycle. The purine nucleoside cycle can generate fumarate from the degradation of purine nucleotides, and this fumarate can be used to replenish intermediates in the citric acid cycle, which is important for energy production in cells. The purine nucleoside cycle is not involved in the conversion of purines to pyrimidines, inhibiting the formation of AMP from IMP, or inhibiting the citric acid cycle in skeletal muscles.

What Is the Importance of the Purine Nucleoside Cycle