The major difference between D₁ and D₂ dopamine receptor subtypes is that one A) is ionotropic and the other is metabotropic. B) inhibits and the other stimulates adenylyl cyclase and cAMP. C) is found in the CNS and the other is found in the PNS. D) is very rare and the other is very common.

Question

Quizplus · Accepted Answer

The major difference between D1-like receptors (including D₁, which refers to a subtype of D1 dopamine receptors) and D2-like receptors (including D₂, which refers to a subtype of D2 dopamine receptors) is their effect on adenylyl cyclase and cAMP levels. D1-like receptors stimulate adenylyl cyclase, increasing cAMP levels, while D2-like receptors inhibit adenylyl cyclase, decreasing cAMP levels.

The Major Difference Between D1 and D2 Dopamine Receptor Subtypes

The Major Difference Between D₁ and D₂ Dopamine Receptor Subtypes