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You Are Treating 46-Year-Old Man Who Has Suffered a Heart

Question 18

Multiple Choice

You are treating 46-year-old man who has suffered a heart attack. Measurement of his serum cholesterol level indicates it is 500 mg/dL. His father died at 37 years of age from a massive heart attack, and one of his 2 younger siblings also has an increased serum concentration of total cholesterol. This patient most likely has a defect in LDL receptor function associated with familial hypercholesterolemia (FH) . Which of the following additional signs is characteristic in patients with FH?


A) arcus cornea
B) dysostosis multiplex
C) hyperammonemia
D) hypoglycemia
E) renal lithiasis

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