The hydrolysis of ATP to ADP and inorganic phosphate proceeds with a ΔG^0' of −7kcal/mol. The hydrolysis of phosphocreatine has a ΔG^0' of −10kcal/mol. In the reaction catalyzed by creatine kinase (creatine phosphokinase), in the direction of phosphocreatine formation, which of the following is the overall ΔG^0' in kcal/mol? A) −17 B) 17 × TΔS C) −3 D) −3 × TΔS E) +3

Question

Quizplus · Accepted Answer

The overall ΔG^0' for the reaction in the direction of phosphocreatine formation is +3 kcal/mol, as it is the reverse of the hydrolysis of phosphocreatine.

The Hydrolysis of ATP to ADP and Inorganic Phosphate Proceeds