How could you increase the magnitude of inhibitory postsynaptic potentials (IPSPs)generated at a synapse?
A)Increase sodium-potassium pump activity.
B)Increase K⁺ permeability.
C)Increase the influx of calcium.
D)All of the above apply.

Question

Quizplus · Accepted Answer

Increasing K⁺ permeability would lead to hyperpolarization of the postsynaptic membrane, making it less likely for an action potential to fire. This would increase the magnitude of IPSPs. Increasing sodium-potassium pump activity or influx of calcium would not necessarily increase the magnitude of IPSPs.

How Could You Increase the Magnitude of Inhibitory Postsynaptic Potentials