Sequencing eukaryotic genomes is more difficult than sequencing genomes of bacteria or archaea because of
A)the large size of eukaryotic genomes.
B)the large amount of eukaryotic repetitive DNA.
C)the high proportion of G-C base pairs in eukaryotic DNA.
D)A and B only.
E)all of the above.

Question

Quizplus · Accepted Answer

Eukaryotic genomes are larger than bacterial or archaeal genomes and contain a large amount of repetitive DNA, making them more difficult to sequence. The high proportion of G-C base pairs in eukaryotic DNA can also make sequencing more difficult, but this is not as significant a factor as genome size and repetitive DNA content. Therefore, options A and B are correct, but option C is not. Option E is incorrect because option C is not a significant enough factor to make sequencing eukaryotic genomes more difficult.

Sequencing Eukaryotic Genomes Is More Difficult Than Sequencing Genomes of Bacteria