Imagine you've isolated a yeast mutant that contains histones resistant to acetylation.What phenotype do you predict for this mutant?
A)The mutant will grow rapidly.
B)The mutant will require galactose for growth.
C)The mutant will show low levels of gene expression.
D)The mutant will show high levels of gene expression.

Question

Quizplus · Accepted Answer

Acetylation of histones promotes gene expression by allowing chromatin to open up and making the DNA accessible to transcription factors. If the histones in the mutant strain are resistant to acetylation, then gene expression will be low because the chromatin will remain tightly packed and transcription factors won't be able to access the DNA.

Imagine You've Isolated a Yeast Mutant That Contains Histones Resistant