A G-protein receptor with GTP bound to it
A)is in its active state.
B)autophosphorylates its tyrosine residues.
C)will use cGMP as a second messenger.
D)directly affects gene expression.

Question

Quizplus · Accepted Answer

When GTP is bound to a G-protein receptor, it signals that the receptor is in its active state and can bind to and activate downstream effector molecules. This is because GTP binding causes a conformational change in the receptor that allows it to interact with other signaling molecules. Autophosphorylation of tyrosine residues is a process that occurs in receptor tyrosine kinases and is not directly related to G-protein receptors. The use of cGMP as a second messenger is also not specific to G-protein receptors and can be used by other types of receptors. G-protein receptors can indirectly affect gene expression by activating downstream signaling pathways that lead to changes in transcription factor activity.

A G-Protein Receptor with GTP Bound to It