Why is 3% mepivacaine plain associated with a higher number of local anesthetic toxicity reports in children compared with other agents?
A) Lack of vasoconstrictor
B) Higher content of anesthetic drug than lidocaine
C) Longer duration of action than lidocaine
D) More difficult for children to metabolize than other anesthetic drugs

Question

Quizplus · Accepted Answer

Lack of vasoconstrictor in 3% mepivacaine plain contributes to a higher plasma level of the drug due to rapid systemic absorption, increasing the risk of local anesthetic systemic toxicity (LAST) compared to agents with a vasoconstrictor that would slow absorption.

Why Is 3% Mepivacaine Plain Associated with a Higher Number