What causes sickle-cell anemia?
A) complete lack of hemoglobin
B) a form of hemoglobin that is misshaped and thus distorts RBC
C) an extra X chromosome that results in production of too much hemoglobin
D) a defective hemoglobin that prevents the formation of blood clots
E) a single-celled parasite transmitted by a mosquito

Question

Quizplus · Accepted Answer

Sickle-cell anemia is caused by a mutation in the hemoglobin gene, leading to the production of hemoglobin S, which is misshaped. This abnormal hemoglobin causes red blood cells to assume a sickle shape, leading to various complications.

What Causes Sickle-Cell Anemia