Which of the following statements about the major histocompatibility complex (MHC) is true?
A) MHC molecules are expressed on professional antigen-presenting cells such as dendritic cells, macrophages and B cells.
B) MHC molecules do not influence the production of immunoglobulins although they must bind antigens before TCRs will recognise the antigen.
C) MHC molecules are expressed only on activated T-cells to enable recognition of specific antigens.
D) MHC molecules are coded for by the multigene complex, which is located with the variable (V) genes and joining (J) elements rather than the constant (C) gene or diversity (D) elements.
E) The MHC restriction concept is particularly important in modern immunology because it details the categories of antigens capable of binding to MHC molecules.

Question

Quizplus · Accepted Answer

MHC molecules are indeed expressed on professional antigen-presenting cells such as dendritic cells, macrophages, and B cells. These cells present antigens to T cells, which is crucial for the adaptive immune response.

Which of the Following Statements About the Major Histocompatibility Complex