A patient with metastatic cancer has had several fractures secondary to bone metastases. The provider orders denosumab [Xgeva]. What will the nurse teach this patient?
A) Denosumab may delay healing of these fractures.
B) Denosumab should be given subcutaneously every 12 months.
C) Denosumab will improve hypocalcemia.
D) Unlike bisphosphonates, denosumab does not increase osteonecrosis of the jaw (ONJ).

Question

Quizplus · Accepted Answer

Because denosumab suppresses bone turnover, fracture healing may be delayed. Denosumab is given every 6 months. Denosumab can exacerbate hypocalcemia. Denosumab can increase the incidence of ONJ.

A Patient with Metastatic Cancer Has Had Several Fractures Secondary