The presence of Reed-Sternberg cells in lymphatic tissue is diagnostic of
A) rheumatic fever.
B) sickle cell anemia.
C) pernicious anemia.
D) Hodgkin's disease.

Question

Quizplus · Accepted Answer

The initial symptoms of Hodgkin's lymphoma are painless enlargement of the lymph nodes in the neck or mediastinum, fatigue, and pruritus (see Figure 10-59). As the disease progresses, the patient may experience the systemic B symptoms of fever, night sweats, and weight loss. Hodgkin's disease is differentiated from other lymphomas by the presence of a Reed-Sternberg cell in the lymphatic tissue, a large cell with two or more mirror-image nuclei, each with a single nucleolus (see Figure 10-60).

The Presence of Reed-Sternberg Cells in Lymphatic Tissue Is Diagnostic