Which chromosomal gene defect is responsible for Friedrich's ataxia?
A)Chromosome 9
B)Chromosome 11
C)Chromosome 6

Question

Quizplus · Accepted Answer

Chromosome 9 gene defectis responsible for Friedrich's ataxia.
Friedrich ataxia is a degenerative disorder manifested by progressive ataxia. The gene responsible for this condition is located in chromosome 9. It occurs between 5 - 20 years of age. The clinical features include balance disruption, development of scoliosis and a spastic ataxic gait.
Chromosome 11 gene defect leads to ataxia telangiectasia. It is a multisystem disorder characterized by cerebellar ataxia, ocular and cutaneous telangiectasis, and immunodeficiency.
Chromosomal 6 gene defect is responsible for autosomal dominant cerebellar ataxia type I. The clinical features include ataxia, opthalmoplegia, mild dementia, optic atrophy, and spasticity.

Which Chromosomal Gene Defect Is Responsible for Friedrich's Ataxia