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You and Your Fellow Deep-Sea Scientists Have Discovered a New

Question 69

Essay

You and your fellow deep-sea scientists have discovered a new form of marine invertebrate, and are anxious to determine the similarities and differences to animals already characterized.Chemical analysis reveals the following concentrations of permeable cations:
 [on  in] mM out] mMNa+50450K+42020Mg++1060Cl50550\begin{array} { | l | l | l | } \hline \text { [on } & \text { in] } \mathrm { mM } & \text { out] } \mathrm { mM } \\\hline \mathrm { Na } ^ { + } & 50 & 450 \\\hline \mathrm { K } ^ { + } & 420 & 20 \\\hline \mathrm { Mg } ^ { + + } & 10 & 60 \\\hline \mathrm { Cl } ^ { - } & 50 & 550 \\\hline\end{array}
Nernst equation: Eion = 61/z × log [ion]out/[ion]in
-Your studies of the neuromuscular junction reveal that the excitatory neurotransmitter opens a channel permeable to all three cations.Calculate the equilibrium potential for each cation.In which direction will each cation move when the channel is open? Does movement of ions promote muscle depolarization? Explain your answer.

Correct Answer:

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ENₐ+ = 61 × log 450/50 = 58 mV.EK+ = 61 ...

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