The binding of lipophilic messengers, such as steroid hormones, to their receptors triggers
A) adenylyl cyclase activation.
B) cyclic nucleotide formation.
C) G protein inhibition.
D) gene transcription.
E) protein kinase activation.

Question

Quizplus · Accepted Answer

The binding of lipophilic messengers, such as steroid hormones, to their receptors triggers gene transcription. This means that the hormone-receptor complex enters the nucleus and binds to specific DNA sequences, leading to the transcription of specific genes and ultimately, the production of new proteins. The other options (adenylyl cyclase activation, cyclic nucleotide formation, G protein inhibition, protein kinase activation) are all associated with the actions of more hydrophilic messengers, such as neurotransmitters and hormones such as adrenaline, that interact with receptors on the cell surface.

The Binding of Lipophilic Messengers, Such as Steroid Hormones, to Their