Arrange the following events in protein secretion in the proper sequence.
1)The polypeptide chain enters the lumen of the endoplasmic reticulum.
2)A secretory vesicle is formed.
3)A transport vesicle is formed.
4)The polypeptide chain enters the lumen of the Golgi complex.
A) 1, 2, 3, 4
B) 1, 3, 2, 4
C) 1, 3, 4, 2
D) 4, 3, 1, 2
E) 3, 1, 4, 2

Question

Quizplus · Accepted Answer

The polypeptide chain first enters the lumen of the endoplasmic reticulum (1). Then, it is transported to the Golgi complex through a transport vesicle (3). Once inside the Golgi complex, the protein is modified and sorted, and then enters a secretory vesicle (4). Finally, the secretory vesicle fuses with the plasma membrane and releases the protein outside the cell (2). Therefore, the correct sequence is 1, 3, 4, 2, which is represented by choice C.

Arrange the Following Events in Protein Secretion in the Proper