Hypophosphatemia (vitamin D-resistant rickets)is inherited as an sex-linked dominant trait.The relevant gene is found on the X chromosome.What is the expected outcome of a cross between a homozygous recessive woman and a man with hypophosphatemia?
A) All of their daughters and none of their sons exhibit hypophosphatemia.
B) Fifty percent of their daughters and fifty percent of their sons exhibit hypophosphatemia.
C) All of their sons and none of their daughters exhibit hypophosphatemia.
D) Twenty-five percent of their offspring exhibit hypophosphatemia.

Question

Quizplus · Accepted Answer

In a cross between a homozygous recessive woman (xx) and a man with hypophosphatemia (X^H Y), all daughters (X^H x) will inherit the dominant X-linked trait from their father, while none of the sons (xY) will inherit it, as they receive their X chromosome from their mother.

Hypophosphatemia (Vitamin D-Resistant Rickets)is Inherited as an Sex-Linked Dominant Trait